1. General Model Information

Name: Dynamic Energy Budget - toxicity application

Acronym: DEBTOX

Main medium: aquatic+terrstrial
Main subject: (eco)toxicology
Organization level: Organ, Population
Type of model: ordinary differential equations
Main application: research
Keywords: Bioassay, exposure time, No Effect Concentration, LC50, sublethal effects, body growth, reproduction, population growth, profile likelihood function, maximum likelihood estimation


Kooijman, S. A. L. M.

Dept Theoretical Biology, Fac Biology, Vrije Universiteit, de Boelelaan 1087, 1081 HV Amsterdam, the Netherlands

Phone: +31 20 4447130
Fax: +31 20 4447123
email: debtox@bio.vu.nl
Homepage: http://www.bio.vu.nl/thb/research/debtox/


Bedaux, J. J. M. and Luger, M. and Kooijman, S. A. L. M.


DEBtox is a user-friendly software package designed to analyze the results of the standard set of aquatic toxicity tests on the basis of the Dynamic Energy Budget theory: acute and chronic tests on survival, the (37d) fish growth test, the (21d) reproduction test with Daphnia and the (4d) alga growth inhibition test.

II. Technical Information

II.1 Executables:

Operating System(s): Unix, Windows (95,98,NT)

II.2 Source-code:

Programming Language(s): C++

II.3 Manuals:

DEBtox help-files in DEBtox

II.4 Data:

help-files in DEBtox included in download

III. Mathematical Information

III.1 Mathematics

III.2 Quantities

exposure time, external concentration

III.2.1 Input

number of surviving individuals, and/or body lengths, or weights, or number of offspring

III.2.2 Output

parameter estimates, confidence sets, test statistics, graphics

IV. References

Kooijman, S.A.L.M. and Bedaux, J.J.M. 1996. The analysis of aquatic toxicity data. VU University Press. ISBN 90-5383-477-X

Kooijman, S. A. L. M. and Bedaux, J. J. M. 1996 Some statistical properties of estimates of no-effects concentrations. Water Res. 30: 1724--1728

Kooijman, S. A. L. M. and Bedaux, J. J. M. 1996 Analysis of toxicity tests on {\em {D}aphnia} survival and reproduction. Water Res. 30: 1711--1723

Kooijman, S. A. L. M. and Bedaux, J. J. M. 1996Analysis of toxicity tests on fish growth. Water Res. 30: 1633--1644

Kooijman, S. A. L. M. and Hanstveit, A. O. and Nyholm, N. 1996 No-effect concentrations in alga growth inhibition tests. Water Res 30: 1625--1632

Andersen, J. S. and Bedaux, J. J. M. and Kooijman, S. A. L. M. and Holst, H. 2000 The influence of design parameters on statistical inference in non-linear estimation; a simulation study. Journal of Agricultural, Biological and Environmental Statistics 5: 28--48

V. Further information in the World-Wide-Web

VI. Additional remarks

Many context references can be found at http://www.bio.vu.nl/thb The analyses are applications of the Dynamic Energy Budget theory, see http://www.bio.vu.nl/thb/deb
Last review of this document by: Mon Jul 3 19:17:23 2000
Status of the document: Contributed by Kooijman, S. A. L. M.
last modified by Tobias Gabele Wed Aug 21 21:44:41 CEST 2002

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